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DORIS - Diabetic Kidney Disease: Onset and Progression RISk Factors Cohort


DORIS is the abbreviation for “Diabetic Kidney Disease – Onset and Progression Risk Factors Cohort”, the latest upcoming cohort study by Clinical Research Unit. It is the successor of our long-running Diabetic Nephropathy cohort, which has produced more than 20 publications to date. In the next-phase, our aim is to recruit approximately 1920 multi-ethnic patients with Type 2 Diabetes (T2DM) to better understand the determinants of onset and progression of Diabetic Kidney Disease (DKD) in the Singapore population.

DKD is the leading cause of end stage renal disease in Singapore, and an established risk factor for cardiovascular disease and mortality in people with diabetes. Recent data suggest that while major complication related to diabetes (e.g. cardiovascular disease) is declining, the incidence of DKD remains unabated. Through our DORIS cohort, we hope to better understand the range of factors that drive DKD.

Therefore, continue to watch this space for more updates on the DORIS cohort!