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CLINICAL RESEARCH
  • What is FH?
  • Diagnosis & Treatment
Based on global statistics, Familial Hypercholesterolemia (FH) affects approximately
20,000 patients in Singapore but more than 90% are unaware of this condition
and remain undiagnosed! Early diagnosis can allow affected individuals and their
family members to start treatment early and ultimately reduce the risk of getting early
heart attack.
FH leads to early heart disease, the #1 killer in the world
Men with FH have 50% risk of having heart disease by age of 50
Women with FH have 30% risk of having heart disease by age of 60

Based on global statistics, Familial Hypercholesterolemia (FH) affects approximately20,000 patients in Singapore but more than 90% are unaware of this condition and remain undiagnosed! Early diagnosis can allow affected individuals and theirfamily members to start treatment early and ultimately reduce the risk of getting early heart attack.

FH leads to early heart disease, the #1 killer in the world

Men with FH have 50% risk of having heart disease by age of 50. Women with FH have 30% risk of having heart disease by age of 60

You may have FH if you have any of the following symptoms/signs
1. High blood cholesterol
 Total cholesterol >7.5mmol/L or 290mg/dl
 LDL-cholesterol >4.9 mmol/L or 189mg/dl
2. Family history of
 a. High cholesterol or
 b. Early heart attack or
 c. Cholesterol deposit around eyes and under skin
3. Mutation test (clinical research) 

You may have FH if you have any of the following symptoms/signs

1. High blood cholesterol 

 - Total cholesterol >7.5mmol/L or 290mg/dl or LDL-cholesterol >4.9 mmol/L or 189mg/dl

2. Family history of 

A. High cholesterol or B. Early heart attack or C. Cholesterol deposit around eyes and under skin

3. Mutation test (Clinical Research) 

Where can I check my cholesterol levels?

You can get your cholesterol levels checked at any public or private clinics. If you suspect you may have one of the above conditions, discuss with your doctor.

Family screening & early treatment

If you have high cholesterol and test positive for mutation, higher dosage of medication may be required. Lifestyle changes such as healthy diet, exercise and medication can help to reduce the risk of heart attack. Early diagnosis and treatment are available. Take action now and seek medical advice.

If you do a mutation test and discover the mutations, your doctor will share the findings with you and advise your immediate family members to come for testing. Patients with FH mutation have a 50% chance of passing to their children. Early detection will allow you and your affected family members to start medication early and reduce the risk of premature heart attack.