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CLINICAL RESEARCH
  • Science - Translational & Applied Research (STAR) I & II
  • Alexandra Health Researcher Investigator Scientist Enabler (RISE)
  • Center Grant Pitch For Fund
  • KTPH Research Scholarship
  • Alexandra Health Enabling Grant

Science - Translational & Applied Research (STAR) I & II are grants designed to support clinical and translational research that answer specific, targeted research questions; or to perform pilot or feasibility studies. STAR I supports small start-up exploratory studies that may provide preliminary findings for larger research proposals.

STAR II is a follow-on grant offered to successfully completed STAR I projects, based on merit
STAR II is designed to encourage continuing translation of research into patient care.

STAR I & II were previously known as Small Innovation Grants (SIG) I & II.

For FY2017, 10 projects were awarded. Our heartfelt congratulations to the following awardees:

S/N

Principal Investigator

Department

Project

Project Title

1

A/Prof Lim Su Chi

Diabetes Centre

STAR II

Precision Medicine for Diabetes - bringing Cell to Society: the Alexandra Health System (AHS) Monogenic Diabetes Registry

2

Dr Sharon Pek Li Ting

Clinical Research Unit

STAR I

Gene panel to identify genetic causes of hypertriglyceridemia: A pilot study 

3

Dr Zhang Xiao

Clinical Research Unit

STAR I

Pilot study of variants for diabetic nephropathy among early-onset T2DM patients in Singapore - a family-based study 

4

Dr Liu JianJun

Clinical Research Unit 

STAR II

Study of novel risk factors and prognostic biomarkers for stratified management of patients with progressive diabetic kidney disease

5

Dr Kumari Neelam

Ophthalmology and Visual Sciences

STAR I

Genetic determinants of macular pigment in subjects from a Singapore Chinese population: A pilot study

6

Dr Resham Lal Gurung 

Clinical Research Unit

STAR I

Association of Haptoglobin genotype with end stage renal disease, cardiovascular disease and all-cause mortality in type 2 diabetes patients with chronic kidney disease in multi-ethnic Asian population

7

Dr Suresh B Babu

Diagnostic Radiology

STAR I

Gastric Angioembolisation for Obesity Treatment (GAOT)

8

Dr Resham Lal Gurung 

Clinical Research Unit

STAR I

A study to test the strategy of pre-emptive genetic testing using a pragmatic clinical trial approach: A case study on allopurinol on chronic Kidney Disease patients

9 Dr Doreen Tan Su-Yin  Pharmacy  STAR I P2SD: Pharmacokinetic and Pharmacodynamic Study of DOACs in Singapore
10 Dr Serena Low  Clinical Research Unit  STAR I Understanding the Impact of Self-Care, Medication Adherence and Appointment Keeping on Chronic Kidney Disease Progression in Type 2 Diabetes


Researcher Investigator Scientist Enabler (RISE) is a grant scheme that provides funding for a portion of the clinician’s salary commensurate with his/her time spent in research. This funded time will be spent on sharpening clinician’s research capabilities. 

Our heartfelt congratulations to the following FY 2017 awardee:

S/N

Principal Investigator

Department

1 A/Prof Subramaniam Tavintharan Diabetes Centre

2

Dr Kumari Neelam

Ophthalmology & Visual Sciences



Our heartfelt congratulations to the following awardees:

S/N 

Principal Investigator

Department

Project Title

1

Dr. Shahla Siddiqui

Anaesthesia

ICU data base and outcomes Study

2

Ms. Ong Shu Fen

Nurse

Learning needs of hospitalized patients with heart failure in Singapore

3

Dr. Claude Jeffrey Renaud

Renal Medicine

Determination of ceftazidime blood concentration during consecutive fixed dialysis day dosing in stable anuric haemodialysis patients

4

Dr. Ang Juvelito Chua

Urology

Randomized control study of the effect of OTO e-shape belt massage on improving stone clearance in lower pole renal stone after extracorporeal shockwave lithoripsy

5

Dr. Kumari Neelam

Opthalmology

Quality of Life in patients with Myopic Macular Degeneration

6

Dr. James Tan

Orthopaedics

Evaluation of Polycaprolactone (PCL) bioactive film for guided bone regeneration in a micro-pig model: preliminary results

7

Dr. James Tan

Orthopaedics

Healing of acromioclavicular and coracoclavicular ligaments after surgery for acute acromioclavicular joint dislocation: results of MRI evaluation.



Our heartfelt congratulations to the following awardee:

S/N

Principal Investigator

Department

Project Title

1

Dr Ester Yeoh

Medicine

The Utility of Continuous Glucose Monitoring System (CGMS) in Diabetes Patients with Chronic Kidney Disease (CKD)



The Alexandra Health Enabling Grant (AHEG) is designed to support pilot research studies to accumulate preliminary data for competitive grants.

For FY2017, 19 projects were awarded. Our heartfelt congratulations to the following awardees:

S/N Principal Investigator Department Project Title
1 Dr Surej John Psychological Medicine Elevated homocysteine as a cause of depression. A case control study.
2 Dr Zhang Xiao Clinical Research Unit Effect of lifestyle factors on genome-wide DNA methylation in diabetic nephropathy among T2DM patients in Singapore
3 Dr Edwin Seet Anaesthesia Prospective observational study to compare the accuracy of a novel mobile phone app-based pulse oximetry system with a proprietary marketed pulse oximetry (Konica Minolta Pulsox-300i) in 20 patients suspected of OSA.
4 Dr James Tan Orthopaedic Surgery The impact of bone tunnel diameter on iatrogenic clavicle and coracoid process features in Anatomic Coracoclavicular Ligament Reconstruction: A biomechanical study using 3D printed bone models
5 Dr Anton Cheng General Surgery Continuous glucose monitoring in post-bariatric surgery patients at 1 year of follow-up
6 Dr Angela Moh Clinical Research Unit Contribution of adipose tissue inflammasomes to obesity and type 2 diabetes in obese individuals
7 Mr Melvin Wong Clinical Research Unit The association of inflammasomes and Type 2 diabetes complications in SMART2D cohort
8 Dr Kumari Neelam Ophthalmology and Visual Sciences Impact of antioxidant carotenoids on novel inflammatory markers in predicting diabetic macular edema 
9 Dr Justin Tang Cardiology Identifying Genetic Variants in Familial Hyperlipidemia Patients Presenting With ST Elevation Myocardial Infarction
10 NC Shao Yanli Diabetes Centre The Effect of Fasting During Ramadan on Ketonemia in Muslim Patients with Type 2 Diabetes on Sodium-glucose Co-transporter-2 Inhibitors
11 Dr Serena Low Clinical Research Unit A study on the impact of chronic disease management in taxi drivers
12 Dr Sharon Pek Clinical Research Unit Use of quantitative thermal sensory testing and Ipswich Touch Test in patients with diabetic peripheral neuropathy
13 Dr Resham Gurung  Clinical Research Unit Integrated genomics and metabolomics approach to identify novel biomarker for rapid progression of chronic kidney disease in type 2 diabetes patients
14 Ms Sylvia Clinical Research Unit Rate of telomere shortening and renal damage in type 2 diabetes patients - a longitudinal study in the SMART2D cohort 
15 Ms Michelle Lin Clinical Research Unit Prospective study of circulating Growth-Differentiation Factor-15 with Peripheral Arterial Disease in patients with Type 2 Diabetes after angioplasty/endarectomy
16 Dr Raymond Chung Diagnostic Radiology Men's Health: Prostate Artery Embolisation
17 Mr Jonathon Khoo Healthcare Analytics Unit Shared Medical Appointments for Diabetic Patients in a Singaporean Context
18 Dr Liu Jianjun Clinical Research Unit Association of hyperglucagonemia with chronic kidney disease in patients with type 2 diabetes
19 Dr Liu Jianjun Clinical Research Unit Association of urine oxidative stress biomarkers with fumarate and CKD progression in patients with type 2 diabetes


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