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CLINICAL RESEARCH
  • Metformin Research Study
  • Diabetes Study
  • SMART2D Study
  • Diabetes Kidney Disease Study
  • Monogenic Diabetes Study
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Title:

Metformin Research Study

Description:

Metformin is one of the best treatment for Type 2 Diabetes, but it does not agree with everyone. We are looking to see if there is anything special in the genes of patient who respond to Metformin treatment differently.

Eligibility:

a. Age 21 to 80 years old
b. Have Type 2 Diabetes
c. No History of Cancer and/or gastrointestinal diseases

When taking Metformin:
1. Have stomach-related problems
2. Had to completely stop taking it
3. Had to take Meformin XR instead

Contact:

Tel: 96430698 
(Mon-Fri, 9am - 12pm or 1pm - 5pm)



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Title:

Diabetes Research Study

Description:

We are looking for volunteer for a 3 years study to find out which of two treatment processes is better at treating Type 2 Diabetes in overweight patient: Surgery or the best medical treatment.

Eligibility:

a. Type 2 diabetes for less than 10- years
b. Age 21 – 65 years old
c. BMI between 27 and 32
d. Willing to have either surgery or the best medical treatment
e. Not pregnant nor planning to get pregnant for the next 3 years

Contact:

Tel: 66023169 



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Title:

SMART2D Research Study

Description:

We are calling for research volunteers who have taken part in the diabetes study in 2011-2014 organised by Khoo Teck Puat Hospital's Clinical Research Unit to participate in a follow-up study. This research investigates the risk factors affecting blood vessel function, eye, kidney and foot complications in people with Type 2 diabetes.

Eligibility:

a. Participants of our previous study
b. Have Type 2 Diabetes
c. Not pregnant

Contact:

Tel: 81289442 
(Mon-Fri, 9am - 12pm or 2pm - 4.30pm)



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Title:

Diabetes Kidney Research Study

Description:

DKD is a common diabetic complication which affects the kidneys. Over time, kidney function is lost, leading to the need for dialysis. DKD patients commonly experience a loss in their quality of life.

Research has shown that DKD tends to occur more frequently within families with a history of DKD. This pattern may be caused by a shared lifestyle among family members. This includes shared diet and behavior.

Eligibility:

a. Families with a strong history of Type 2 Diabetes
b. 5 direct family members must take part
c. All participants must be aged between 21 to 99 years old

Contact:

Tel: 91135891 
(Mon-Fri, 9am - 12pm or 2pm - 4.30pm)



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Title:

Monogenic Diabetes Study (MODY)

Description:

MODY (Maturity-Onset Diabetes of the Young) is a form of monogenic diabetes that is caused by a single gene abnormality (mutation). Our research study aims to identify potential MODY patients for genetic testing in order to determine the mutation which will help doctors better understand the disease and treat the patients. The MODY Registry provides a platform to gather information for further studies of monogenic diabetes that will serve the interests of patients and healthcare providers.

Principal Investigator:

Associate Professor Lim Su Chi
Senior Consultant, Diabetes Centre
Clinical Director, Clinical Research Unit
Khoo Teck Puat Hospital

Recruitment Period:

Now till March 2020

Eligibility:

a. Age 6-99 years old
b. Diabetes diagnosed at 25 years old or less
c. Additional criteria applies (eligibility to be confirmed by study team)

Cost:

For eligible and consented participants:

a. No charge for tests performed as part of the study
b. One-time transport reimbursement provided

Contact:

Tel: 97552352 (Jessie Fong)
(Mon-Fri, 9am - 12pm or 2pm - 4.30pm)